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Klonopin vs Xanax: What’s the Differenc What’s the Difference Between Klonopin and Xanax? Like other benzos, Clonazepam and Xanax both have a similar effect on the body. These are among the most commonly abused benzos. They’re both CNS depressants that interact with the neurotransmitter GABA. They both reduce symptoms of anxiety. And, both produce a calming effect that can help the body slow down a bit. Despite their similarities, though, they’re generally prescribed to treat different conditions. Klonopin, for instance, is mostly used to combat panic attacks and seizures. Xanax, on the other hand, is primarily used to treat anxiety. However; both medications are often prescribed by doctors to treat insomnia . Also, these drugs affect the body differently in terms of half-life . Xanax is fast-acting. It is released into the bloodstream almost immediately. And, the body starts to push it out of your system in about one to two hours. The mentalhealth.gov medicine’s effects are intense and short-lived. Usually, the drug starts to wear off in about four to six hours. Klonopin is slower acting than Xanax and it is not as powerful. It requires more time for the drug to take effect because the half-life is greater.

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